If you’re looking for the perfect 1-week Vietnam itinerary that combines cultural immersion, authentic local life, and riverfront relaxation, AmaWaterways’ Riches of the Mekong cruise is an amazing choice. Sailing from Siem Reap to Ho Chi Minh City, this journey unveils the timeless charm of Southeast Asia, taking travelers deep into the heart of Cambodia and southern Vietnam.
For anyone planning a 7-day Vietnam itinerary, this cruise is the best way to explore the Mekong Delta, discover centuries-old traditions, and experience the local culture up close, all while enjoying AmaWaterways’ signature comfort and service.
About AmaWaterways

AmaWaterways is known worldwide for its exceptional river cruise experiences across Europe, Africa, and Asia. The line offers an upscale yet welcoming atmosphere, elegant accommodations, and a focus on immersive cultural exploration.
Their Mekong River itineraries provide a fascinating look at life along one of the world’s most storied waterways. Onboard the AmaDara, guests enjoy spacious staterooms, regional cuisine, daily excursions with expert local guides, and enriching cultural performances.
Whether you’re interested in history, cuisine, or authentic encounters with local villages, AmaWaterways offers a good value and a great way to experience Southeast Asia.
7-Day Vietnam & Cambodia Itinerary: Riches of the Mekong
Day 1 – Siem Reap to Kampong Cham (Embarkation)

Begin your journey in Siem Reap, the gateway to Angkor Wat, a UNESCO World Heritage Site and one of the best places in Southeast Asia for history buffs. After a short drive to Kampong Cham, embark on the luxurious AmaDara and meet your fellow travelers over a Welcome Dinner.
Travel Tip: Arrive in Siem Reap at least a day early so you have enough time to explore the ancient temples or enjoy a street food tour before the cruise begins.
Day 2 – Angkor Ban & Oknhatey Village

Step back in time as you take a walking tour of Angkor Ban, one of the few Cambodian villages untouched by modern development. The local life here offers a first-hand look at traditional wooden homes and family farms. In the afternoon, visit Silk Island (Oknhatey Village) to watch artisans weaving by hand, an age-old craft passed down for generations.
Day 3 – Phnom Penh
Arrive in Phnom Penh, Cambodia’s capital city, and explore the Royal Palace, National Museum, and the Silver Pagoda. These are must-see historical sites for anyone interested in the region’s rich history.
In the afternoon, learn about Cambodia’s more recent past with a visit to the Killing Fields and the Genocide Museum.
Those who prefer a lighter experience can explore the Central Market, a great place to find local crafts and food stalls serving authentic dishes.
Day 4 – Oudong & Phnom Penh
Visit Oudong, Cambodia’s former capital city, where you’ll take part in a peaceful Buddhist blessing ceremony at a local monastery. Later, hop on a tuk tuk for a city tour of Phnom Penh, passing colonial architecture, narrow streets, and lively local markets, a great way to see local culture firsthand.
Day 5 – Cruising into Vietnam

Spend a relaxing day aboard as the ship crosses the border into Vietnam. Enjoy the scenic views of the Mekong River, dotted with small islands and traditional fishing villages that reflect everyday local life in southern Vietnam.
This stretch of the cruise is the perfect time to unwind and appreciate the natural beauty of the river and its surroundings.
Day 6 – Tan Chau & Sa Dec

In Tan Chau, take a trishaw ride through town, stopping at silk and rattan workshops to meet local artisans. Alternatively, venture into Tra Su Forest for a peaceful boat ride through lotus-filled waterways and lush greenery, a natural wonder of the Mekong Delta.
Later, explore Sa Dec, a must-visit destination for literature lovers. Visit the “Lover’s House,” made famous by French author Marguerite Duras, or enjoy the colorful local market and Cao Dai Temple.
Travel Tip: Try a local banh mi or bun cha for lunch; both are authentic Vietnamese street food favorites.
Day 7 – Cai Be & Ho Chi Minh City

On your final full day, visit local workshops in Cai Be to see how rice paper and coconut candy are made, a great way to understand traditional craftsmanship in southern Vietnam. Then, transfer to Ho Chi Minh City, formerly known as Saigon.
Take a short walk around the city centre, enjoy ca phe trung (a Vietnamese drink traditionally prepared with egg yolks, sugar, condensed milk and coffee), and reflect on your incredible week along the Mekong River.
What’s Included

AmaWaterways’ Riches of the Mekong cruise is thoughtfully designed to offer a seamless, all-inclusive journey that blends world-class comfort with authentic exploration. Over seven nights, guests enjoy luxury accommodation in spacious twin-balcony staterooms featuring flat-panel entertainment systems, a mini-fridge, desk, sitting area, and bottled water replenished daily, perfect for relaxing after a day of adventure along the river.
Life on board is as relaxing as it is enriching. Travelers are cared for by a highly trained Cruise Manager throughout both the cruise and land portions of the trip. The ship’s amenities include a Sun Deck with pool, fitness room, and three spas, as well as the Saigon Lounge, an inviting space with panoramic views and a full bar. Each evening brings cultural entertainment and performances, adding a local touch to the onboard experience.
Dining is a highlight of the journey, with regionally inspired cuisine prepared from locally sourced ingredients and served in a variety of venues. Guests can indulge in exquisite meals at The Chef’s Table specialty restaurant, enjoy a Welcome Cocktail and Dinner, and savor unlimited wine with lunch and dinner alongside complimentary local beer, house-brand spirits, and soft drinks. Snacks and refreshments are also available daily in the Main Lounge.
Every destination along the Mekong offers immersive tours led by knowledgeable local guides. Whether you prefer gentle, regular, active, or late-riser options, excursions are designed to suit every pace and interest. Personal headsets make it easy to follow along during guided tours, and those who book air with AmaWaterways can also enjoy convenient airport transfers.
With these inclusions, the Riches of the Mekong cruise offers outstanding value, delivering a luxurious and effortless way to experience the natural beauty, fascinating culture, and historic treasures of Vietnam and Cambodia.
Central Vietnam Extension: Hoi An & Hue

If you have extra time, add AmaWaterways’ 4-night Central Vietnam extension, which takes you to the ancient town of Hoi An and the Imperial City of Hue.
- Fly from Ho Chi Minh City to Da Nang Airport, a short flight that opens up the central coast’s beautiful beaches and natural beauty.
- In Hoi An, explore the Old Town, a UNESCO World Heritage Site, filled with narrow streets, colonial architecture, and lantern-lit nights. Take a cooking class and enjoy local food stalls serving flavorful local dishes.
- Continue to Hue, where you’ll visit the Hue Historic Citadel, Thien Mu Pagoda, and the tomb of Emperor Minh Mang, sites that captivate history buffs and highlight Vietnam’s royal past.
- This short trip beautifully complements your Vietnam itinerary, giving you a full picture of the entire country, from southern Vietnam’s river life to central Vietnam’s imperial heritage.
Optional Bangkok Pre-Extension

If you’d like to explore more of South East Asia, AmaWaterways also offers a Bangkok pre-extension. You’ll visit the Grand Palace, the Temple of the Emerald Buddha, and enjoy a boat trip through the city’s historic canals. Bangkok’s night markets and street food make it a great place to start your first trip to the region.
Best Time to Visit Vietnam & Cambodia

The best time to visit Vietnam and Cambodia is during the dry season, from November to April, when rainfall is minimal, humidity levels are lower, and daily temperatures are warm but comfortable. This period offers ideal conditions for river cruising along the Mekong, as water levels are steady and the landscapes are at their most picturesque. You’ll enjoy clear skies for exploring temples, floating villages, and countryside markets, and evenings are pleasantly mild, perfect for dining on deck or strolling through riverside towns.
Traveling during this season also means you’ll experience lively local festivals, such as Tet (Vietnamese New Year) in January or February and Khmer New Year in April, which provide a fascinating glimpse into the region’s culture and traditions.
While the dry season is the most popular time to visit, the shoulder months of May and October can also be rewarding, with fewer crowds and lush green scenery following the rains. Though short tropical showers are more common, they’re usually brief and followed by sunshine, allowing plenty of time for sightseeing and excursions.
Overall, planning your Mekong River cruise between November and April ensures the smoothest sailing experience and the best opportunity to see the natural beauty and cultural highlights of Vietnam and Cambodia at their finest.

AmaWaterways’ Riches of the Mekong is one of the best 7-day Vietnam itineraries for travelers who want to experience both local life and luxury. It’s perfect for those who want to experience Vietnam and Cambodia beyond the surface, meeting local communities, exploring floating markets, ancient temples, and timeless villages, without the stress of planning every detail.
Whether it’s your first-time visit or your favourite place to return to, this Vietnam trip with AmaWaterways promises an unforgettable look at the heart of Southeast Asia.
READY TO PLAN YOUR NEXT RIVER CRUISE?
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